| Date | Opponent | Location | Time/Outcome |
| 10/27/04 | Meet The Rams Media Day | Winston-Salem, NC | 6:00 PM |
| 11/03/04 | Preseason Press Conference | Winston-Salem, NC (Gaines Rm. 108) | 11:00 AM |
| 11/08/04 | Radford (Exhibition) | Radford, VA | L, 62-45
Recap | Final Stats |
| 11/16/04 | Lenoir-Rhyne | Hickory, NC | L, 77-72
Recap | Final Stats |
| 11/19/04 | Bluefield State (Lady Rams Classic) | Winston-Salem, NC | W, 76-54
Recap | Final Stats | Gametracker |
| 11/20/04 | St. Paul's (Lady Rams Classic) | Winston-Salem, NC | W, 77-51
Recap | Final Stats | Gametracker |
| 11/23/04 | Wingate | Winston-Salem, NC | W, 54-44
Recap | Final Stats | Gametracker |
| 11/26/04 | Clark-Atlanta | Atlanta, GA | W, 65-64
Recap | Final Stats |
| 11/27/04 | Paine | Atlanta, GA | W, 74-62
Recap | Final Stats |
| 11/29/04 | Queens (N.C.) | Charlotte, NC | W, 89-52
Recap | Final Stats |
| 12/15/04 | Wingate | Wingate, NC | L, 78-53
Recap | Final Stats |
| 12/17/04 | Catawba | Winston-Salem, NC | W, 69-56
Recap | Final Stats | Gametracker |
| 12/30/04 | Francis Marion (USC-Upstate Tourney) | Spartanburg, SC | W, 54-47
Recap | Final Stats |
| 12/31/04 | USC-Upstate (USC-Upstate Tourney) | Spartanburg, SC | L, 81-78
Recap | Final Stats |
| 01/04/05 | Virginia Union | Winston-Salem, NC | L, 69-59
Recap | Final Stats | Gametracker |
| 01/06/05 | Elizabeth City State | Elizabeth City, NC | W, 70-61
Recap | Final Stats |
| 01/11/05 | Saint Augustine's | Raleigh, NC | W, 68-64
Recap | Final Stats |
| 01/20/05 | Shaw | Winston-Salem, NC (LJVM Annex) | L, 89-71
Recap | Final Stats |
| 01/22/05 | St. Paul's | Lawrenceville, VA | Postponed |
| 01/25/05 | Virginia State | Winston-Salem, NC (LJVM Annex) | L, 68-64
Recap | Final Stats |
| 01/27/05 | Johnson C. Smith | Charlotte, NC | L, 73-63
Recap | Final Stats |
| 01/29/05 | Bowie State | Winston-Salem, NC | L, 74-70
Recap | Final Stats | Gametracker |
| 02/01/05 | Fayetteville State | Fayetteville, NC | L, 83-76 (OT)
Recap | Final Stats |
| 02/03/05 | St. Paul's | Lawrenceville, VA | W, 68-59
Recap | Final Stats |
| 02/05/05 | North Carolina Central | Durham, NC | L, 76-71 (2OT)
Recap | Final Stats |
| 02/08/05 | Saint Augustine's | Winston-Salem, NC (LJVM Annex) | L, 63-61
Recap | Final Stats |
| 02/10/05 | Livingstone | Winston-Salem, NC | W, 55-53
Recap | Final Stats |
| 02/12/05 | Johnson C. Smith | Winston-Salem, NC | W, 70-59
Recap | Final Stats | Gametracker |
| 02/15/05 | Livingstone | Salisbury, NC | L, 56-51
Recap | Final Stats |
| 02/20/05 | Fayetteville State | Winston-Salem, N.C. (LJVM Coliseum) | L, 83-82
Recap | Final Stats | Gametracker |
| 02/22/05 | North Carolina Central | Winston-Salem, NC (LJVM Coliseum) | L, 72-62
Recap | Final Stats | Gametracker |
| 02/28/05 | Virginia Union (CIAA Tournament) | Raleigh, NC (RBC Center) | W, 66-55
Recap | Final Stats | Quotes | Gametracker |
| 03/01/05 | Fayetteville State (CIAA Tourney) | Raleigh, NC (RBC Center) | W, 70-60
Recap | Final Stats | Quotes | Gametracker |
| 03/04/05 | Elizabeth City State (CIAA Tourney) | Raleigh, NC (RBC Center) | L, 61-60
Recap | Final Stats | Quotes |
